00:02:05.000So if that's something you're not up for, this would be one to skip.
00:02:08.820And if it's something you are up for, welcome.
00:02:10.880If you're not up for hearing conversations about bread, this is the episode for you.
00:02:15.700Because we're going to have zero carbohydrates in this entire episode.
00:02:19.860So Mike, tell me what you know about the keto diet.
00:02:22.160Very little, honestly, because I've ignored this entire thing because it's just the Atkins diet again, isn't it?
00:02:28.900It's like a much more restrictive version of the Atkins diet.
00:02:33.080The Atkins diet, famously easy to live on in the long term.
00:02:38.280So, like, yes, it is like the Atkins diet and like Ed McMahon's diet book.
00:02:43.580And like pretty much all the diets that we talk about fall into a handful of categories.
00:02:49.000One is low fat, which has heavy overlap with low calorie.
00:02:53.640There's another category that is low carb diets.
00:02:56.880There's another category that is like cleanses and sort of crash diets that are designed to be very short term.
00:03:04.200And then there's another one that is just like restricting food groups like nightshades or like restriction based on things other than macronutrients.
00:05:25.760So like you keep trying to get like shoehorn more fat into your diet.
00:05:31.460It does sound harder than the Atkins diet because in the Atkins diet, you only had to remember one thing, like no carbs.
00:05:37.140So it's like have a Big Mac, but take off the bun.
00:05:39.860Whereas with keto, it seems like you're trying to maximize fat and then like it's OK to have little bits and pieces of other stuff.
00:05:47.360It just seems like there's more of a sort of like three dimensional calculation going on.
00:05:51.920Absolutely. So like there are some sort of mnemonics and some devices that folks come up with to help remember all of the rules about keto.
00:06:00.380So, like, one of the big ones is folks will talk about, like, only vegetables that grow above ground.
00:06:06.560No root vegetables, no onion or very limited onion.
00:06:11.320No squash, even though that grows above ground.
00:06:59.180That is something that folks who are keto devotees will refer to as dirty keto.
00:07:04.800So they're like, you're technically doing it, but you're doing it wrong.
00:07:08.500I love it when diets start engaging in weird gatekeeping.
00:07:11.200As soon as you create something, it's like all of a sudden you have to say, like, you're not doing it right.
00:07:16.420Like, that's the first thing to happen.
00:07:17.840Yep. Well, I mean, like, we've also talked about this, that quite a bit of sort of the social aspect of dieting is like a performance of like, this is the kind of person I am.
00:08:16.700Quote, essentially, the ketogenic diet promotes a pseudo fasted state.
00:08:21.180After three to four days of fasting or following a very low-carbohydrate diet, the body, deprived of dietary sugar and starch, reduces insulin secretion and switches to primarily burning fat for fuel.
00:08:35.820The resulting overproduction of acetyl COA leads to formation of ketones in a process known as ketogenesis.
00:08:45.600Whereas the brain can't use fatty acids for fuel, ketones can cross the blood-brain barrier, providing fuel to the typically glucose-hungry brain as well as to other tissues.
00:08:57.760The transition to physiological or nutritional ketosis usually takes about a week.
00:09:02.460So it's basically you're depriving your brain of carbohydrates, which it usually needs.
00:09:08.720And then your body, in response to that, starts making this other kind of brain food called ketones and starts feeding that to your brain.
00:09:16.220And it takes about a week to sort of transition.
00:09:55.460Yeah. So you pee onto these strips to tell you how many ketones there are in your urine.
00:09:59.920What I've read from the research is like that isn't actually a measure of anything because you shouldn't like it doesn't really matter if they're present in your urine.
00:10:07.880It matters if they're present in your blood.
00:10:09.580So the only way to really test for that is with a blood test.
00:13:09.120So by the 19-teens and 20s, fasting in particular is being popularized for everyone by a couple of doctors who are disciples of this guy who is absolutely not a fucking doctor, whose name is Bernard McFadden.0.95
00:25:57.120Very into Alice and Janney being in this.
00:25:59.420So here's the interesting thing about this is that there's this whole through line of like modern medicine doesn't have the answers and blah, blah, blah.
00:26:07.560And it's like, no, no, this was medically studied.
00:42:28.500I wonder if we have some sort of pithy phrase that we use when diets peak in interest.
00:42:33.980I will say I did some searches for Joe Rogan Keto just to see sort of what's out there.
00:42:39.600And the like top responses were keto food and supplement brands who've done some SEO being like, we're Joe Rogan's favorite keto supplement.
00:42:51.320So like overwhelmingly, the responses were folks figuring out how to market their product around Joe Rogan in particular.
00:42:59.560It's also the perfect fad diet structure because it's like cleanses.
00:43:02.700It's almost impossible to maintain.0.94
00:43:40.680But what is often missing from conversations about the keto diet,
00:43:44.640even in the research honestly is discussion of sort of the risks of the diet yeah the laundry
00:43:51.860list of considerations is sort of astonishing so i found a bunch of research and a bunch of
00:43:57.580popular media articles that were like here are like three or five things to know before you go
00:44:04.000on the keto diet all of those listed different things and almost all of them said you don't
00:44:11.380really have to worry because you'll be losing weight and isn't that what matters the most oh
00:44:14.500my god including in the research like including researchers are saying like it's not that big a
00:44:19.300deal because you're losing weight and really what you need to do is lose weight so here are the0.88
00:44:22.920things that they're saying is are not that big a fucking deal the first one that folks do talk0.94
00:44:27.960about quite a bit more is something called the keto flu is this a phrase you've heard before0.96
00:44:32.200no the sort of theory is that this is sort of like you get run down while your body is figuring out
00:44:38.620how to operate without glucose. Side effects include dizziness, fatigue, headaches, nausea,
00:44:47.020vomiting, insomnia, lowered tolerance for exercise, lethargy, and constipation.
00:44:53.200Another one that folks talk about a fair amount is bad breath. Folks will describe it as being
00:44:58.060kind of fruity, but like bad fruity. Bad fruity? That's what people called me in high school.
00:45:03.580I was going to say that's how I identify, bad fruity.
00:45:06.800There is also a phenomenon that is mostly anecdotal, so there hasn't been research into it, but I wanted to include it because it's so gross.
00:46:00.500In addition to losing fat on the keto diet, folks will lose muscle mass.
00:46:06.480So folks do lose fat, like lose body fat, but they also lose more muscle mass than on other diets, which is really interesting to me given that it is sort of popularized by like shred bros like Joe Rogan, right?
00:46:21.960But keep in mind, they're also disgusting to make out with or go down on and lethargic and irritable and maybe vomiting.
00:46:30.500So in addition to all of this, the keto diet has been linked to really significant liver, kidney and gallbladder problems because all three of those things are processing macronutrients in your body and all three of those things can get really fucked up by radically changing how much work they have to do.
00:46:52.720So if you have any liver issues like fatty liver disease, like cirrhosis, like whatever, adding so much fat to metabolize could make those worse.
00:47:05.200And if you don't have them, it can increase your risk for future liver issues.
00:49:39.960So this is from Prevention Magazine, quote,
00:49:42.280Cutting out carbs can cause the brain to release a chemical called neuropeptide Y, which tells the body that we need carbs.
00:49:51.900When we don't get those carbohydrates our body needs, this chemical builds up and can intensify cravings, which can increase the risk of developing disordered eating patterns.
00:50:01.620It has nothing to do with not having enough willpower.
00:50:05.500It's more to do with the body's biological response to deprivation, says Laura Yu, a registered dietitian.
00:50:12.680Yeah, I mean, there's a reason why we have these three macronutrients and like most, you know, there's vast diversity between diets around the world.
00:50:22.020Like different world regions have different crops.
00:50:24.220But the ratio of these different macronutrients is like reasonably consistent.
00:50:28.740and there's probably like a biological reason for that yeah there totally is and this level of
00:50:35.180fixation on which food groups you can or can't eat for optimal health and for weight loss and
00:50:41.600all of that sort of stuff is in the scope of human history like extraordinarily recent yes yes so
00:50:48.420here is the final side effect are you ready early death this is a quote from health magazine quote
00:50:55.680A 25,000-person study presented at the European Society of Cardiology Congress suggested that people on the lowest-carb diets had the highest risk of dying from cancer, cardiovascular conditions, and all other causes.
00:51:13.040Another study published this month in The Lancet also found that people who followed diets that were low in carbs and high in animal proteins, typical of the keto diet, had a higher risk of early death compared to those who consumed carbs in moderation.
00:51:29.060Yes, but most of that risk is because they're listening to Joe Rogan and they fall off of a ladder.
00:51:34.880They're just not paying attention to their surroundings.
00:51:36.660It was really overwhelming to me to me to look at these like aside from Fen Fen, we have not looked at a diet or a cleanse that has been like one of the side effects is you might die from like four different things.
00:52:03.580So U.S. News & World Reports every year ranks the best and worst diets for overall health via a panel of doctors and dieticians and other health care providers.
00:52:43.700The other thing that I will say that we haven't really touched on much here is – and this is just anecdotal from my own personal experience on this diet.
00:52:52.300I was astonished at how costly it was and how time-consuming it was.
00:54:37.380So if you're on, I was going to say, so if you're on the keto diet, stay on it.
00:54:41.220But no, if you're on the keto diet, stop.
00:54:46.140I mean, listen, I'm not here to tell you don't eat the keto diet.0.99
00:54:49.980And even if I did, fucking glass house, I did it.
00:54:52.960This is a place where it's really worth sort of digging in on what the actual research actually says and like straight up like doing your own research into some primary sources.0.95
00:55:04.900And also anyone who is trying to sell you on this diet, first check whether or not they are wearing shoes.